In the first episode of Insecure, Issa says that Drake “just gets us” when Daniel says that every college educated girl loves Drake. After that, every episode of Insecure that season featured a Drake lyric. You can find a comprehensive list here.
During the first episode of Season 2, Lawrence ask where the Frank Ocean pillow was, and Issa said it was missing. It was revealed that Issa spilled something on it, so it is no longer on the couch. On the second episode, Kelly says the lyric “working at the Pyramid tonight” from Frank Ocean’s “Pyramid” from the Channel Orange album. Issa also has a Frank Ocean phone case.
While there has only been two episodes so far, I’m guessing that Frank Ocean lyrics will be an Easter Egg to seek out every episode this season. It is also important to note that the commercial promoting the second season featured the Calvin Harris song “Slide” featuring Frank Ocean